Testing Requirements for Insurance Coverage
Comprehensive Familial Cancer (CGx) Panel
This 193 gene panel analyzes genes related to familial cancer to identify risk of developing cancers in families.
Testing Requirements
- MAJOR DIAGNOSIS - 1+ REQUIRED
- FAMILY HISTORY (IF KNOWN)
MAJOR DIAGNOSES
- Bladder Cancer
- Blood Cancer
- Brain Cancer
- Breast Cancer
- Cervical Cancer
- Colorectal Cancer
- Esophageal Cancer
- Head/Neck Cancer
- Kidney Cancer
- Liver Cancer
- Lung Cancer
- Metastatic Cancer
- Ovarian / Uterine Cancer
- Pancreatic Cancer
- Prostate Cancer
- Sarcoma
- Stomach Cancer
- Testicular Cancer
- Thyroid Cancer
CANCER SYNDROMES
- Cowden Syndrome
- Familial Adenomatous Polyposis
- Hereditary Breast-Ovarian Cancer
- Li-Fraumeni Syndrome
- Multiple Endocrine Neoplasia
- Nevoid Basal Cell Carcinoma Syndrome
- Renal Cell Cancer
- Von Hippel-Lindeau Disease
Cardiopulmonary Disorders (CPUL) Panel
This 258 gene panel analyzes genes associated with cardiopulmonary disorders, cardiomyopathies, cardiac arrhythmias, Noonan Syndrome, pulmonary fibrosis, and congenital heart diseases.
Testing Requirements
- MAJOR DIAGNOSIS - 1+ REQUIRED
- FAMILY HISTORY (IF KNOWN)
MAJOR DIAGNOSES - CARDIAC
- Angina
- Arrhythmia
- Cardiomyopathy
- Cerebrovascular Disease
- Congenital Heart Disease
- Coronary Artery Disease
- Dyslipidemias
- Myocardial Infarction
- Heart Failure
- Hypertension
- Pericarditis
- Peripheral Artery Disease
- Pulmonary Embolism
- Rheumatic Fever
MAJOR DIAGNOSES - PULMONARY
- Alpha -1 Antitrypsin Deficiency
- Asthma
- Bronchiectasis
- Chronic Obstructive Pulmonary Disease
- Bronchitis
- Emphysema
- Cystic Fibrosis
- Obstructive Sleep Apnea
- Pulmonary Fibrosis
- Sarcoidosis
- Pneumonia
- Respiratory Synctial Virus
- Tuberculosis
- Abnormal Results of PFTs
Comprehensive Eye (EYE)
This 323 gene panel analyzes genes related to eye disorders such as blindness, color blindness, retinitis, pigmentosa, nystagmus, age-related macular degeneration, cataracts, glaucoma, microphthalmia, severe reduction of visual acuity, and many more.
Testing Requirements
- MAJOR DIAGNOSIS - 1+ REQUIRED
- FAMILY HISTORY (IF KNOWN)
MAJOR DIAGNOSES
- Retinitis pigmentosa
- Leber congenital amaurosis
- Macular degeneration
- Achromatopsia
- Oguchi disease
- North Carolina macular dystrophy
- Best disease
- Nystagmus
- Stargardt disease
- Cone-rod dystrophy
- Cataracts
- Bardet-Biedl syndrome
- Corneal dystrophy
- Usher syndrome
- Diabetic retinopathy
- Optic nerve hypoplasia
- Choroideremia
- Inherited strabismus
- Glaucoma
- Batten disease
- Extreme hyperopia
- X-linked retinoschisis
- Misshaped corneas
- Pattern dystrophies
Diabetes (DO)
This 61 gene panel analyzed genes related to Type I and Type II Diabetes Mellitus disorders.
Testing Requirements
- MAJOR DIAGNOSIS - 1+ REQUIRED
- FAMILY HISTORY (IF KNOWN)
MAJOR DIAGNOSES
- Type I Diabetes
- Type II Diabetes
- Monogenic diabetes
- Hepatocyte nuclear factor-4-alpha
- Insulin promoter factor 1
- Hepatocyte nuclear factor-1-beta
- Neurogenic differentiation factor 1
- Beta cell gene defects
- Genetic defects in insulin action
- Genetic defects in mitochondrial DNA
- Wolfram syndrome
- Fulminant diabetes
- Diseases of the exocrine pancreas
- Endocrinopathies
- Gestational diabetes
- Immune mediated diabetes
Immunological, Sarcoidosis, and Immunodeficiency (IMMUNE) Panel
This gene 324 panel analyzes genes related to immunological disease, Primary Immunodeficiency, Sarcoidosis, and autoimmune disorders.
Testing Requirements
- MAJOR DIAGNOSIS - 1+ REQUIRED OR MINOR DIAGNOSIS - 2+ REQUIRED
- FAMILY HISTORY (IF KNOWN)
MAJOR DIAGNOSES
- Alzheimer’s / Dementia
- Celiac Disease
- Chronic Bronchitis
- Chronic Sinusitis
- Crohn’s Disease
- Diseases of Primary Immunodeficiency
- Hashimoto’s Thyroiditis
- Lupus
- Multiple Sclerosis
- Parkinson’s Disease
- Pernicious Anemia
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Sjogren’s Syndrome
- Type I Diabetes
- Ulcerative Colitis
MINOR DIAGNOSES
- Digestive problems associated with Crohn’s
- Ectopic Dermatitis
- Eczema
- Psoriasis
- Seborrheic Keratosis
Neurological Disorder, Parkinson’s Disease, Ataxia, and Dementia (NEURO) Panel
This 185 gene panel analyzes genes related neurological diseases, Ataxia, ALS, CMT, Spastic Paraplegia, early onset dementia, and other neurological disorders.
Testing Requirements
- MAJOR DIAGNOSIS - 1+ REQUIRED
- FAMILY HISTORY (IF KNOWN)
- PARKINSON‘S, ALZHEIMER‘S, AND DEMENTIA - UP TO A 3RD DEGREE BLOOD RELATIVE
MAJOR DIAGNOSES
- Alzheimer’s / Dementia
- Anxiety Disorder
- Creutzfeldt-Jakob Disease
- Dementia
- Depression
- Epilepsy
- Huntington’s Disease
- Insomnia
- Lewy Body Disease
- Migraine
- Parkinson’s Disease
- TBI
SYMPTOMS
- Aphasia
- Anger
- Dysphagia
- Hallucinations
- Irritability
- Nervousness
- Repeated falls
- Restlessness
- Tremor
- Unhappiness
- Unsteadiness
- Violent behavior
Comprehensive Pharmacogenomics (PGX) Panel
This panel is testing Targeted SNPs in 46 genes related to drug-response, metabolism, potential risks, dosage, and patient therapeutic plan management.
Testing Requirements
3 PRESCRIPTION MEDS IN THE FOLLOWING CATEGORIES
- Psychiatric
- Pain
- Cardiovascular
- Chemotherapy
- Medications can be in the same or different class
- Must provide the names of all medications
BENEFITS OF PHARMACOGENOMIC TESTING
- Maximizes the intended use of medications and/or treatments
- Reduces the risk of adverse drug reactions
- Reduces the risk of drug-drug interactions
- Potentially decreases the chance of side effects and/or dependency
Respiratory Disease (PULM) Panel
This 162 gene panel analyzes genes related to various respiratory diseases such as asthma, COPD, bronchiectasis, pulmonary arterial hypertension, pulmonary fibrosis, and sarcoidosis.
Testing Requirements
- MAJOR DIAGNOSIS - 1+ REQUIRED
- FAMILY HISTORY (IF KNOWN)
MAJOR DIAGNOSES
- Alpha -1 Antitrypsin Deficiency
- Asthma
- Bronchiectasis
- Chronic Obstructive Pulmonary Disease
- Bronchitis
- Emphysema
- Cystic Fibrosis
- Obstructive Sleep Apnea
- Pulmonary Fibrosis
- Sarcoidosis
- Pneumonia
- Respiratory Synctial Virus
- Tuberculosis
- Abnormal Results of PFTs
Thyroid Disorders and Thyroid Cancer (THY) Panel
This 60 gene panel analyzes genes associated with thyroid disorders.
Testing Requirements
- MAJOR DIAGNOSIS - 1+ REQUIRED
- FAMILY HISTORY (IF KNOWN)
MAJOR DIAGNOSES
- Hyperthyroidism
- Grave’s Disease
- Hypothyroidism
- Hashimoto’s Thyroiditis
- Goiter
- Thyroid Nodule